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How Long For Botox To Work For Migraines. Myobloc is not approved by the fda to treat chronic migraine headaches, but it has a similar mechanism of action and has been shown to relieve migraines in several studies. This article finds that when botox is used as a treatment for lines wrinkles, that onset of efficacy is typically rapid. When you get botox for migraines at the z center for cosmetic health, dr. In studies nearly 50% of patients achieved this goal after 6 months of treatment (2 sets of injections).





